Windows 10

1. Manually unzipped ezQuake to my Quake folder and ran ezQuake.exe
I get this:
Genport I/O initialization failture.
grSstSelect: non-existent SST
Failed to create SDL window: No matching GL pixel format available


2. I tried nQuake installer.

During installation of nQuake with HD textures:

Error extracting "gpl.zip": Error opening output file(s)

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You need to get GLDirect. Then it works